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    Cisco Secure Email Threat Defense

    Email SecurityIntegrated Cloud Email Security (ICES)BEC ProtectionCloud Email Security

    Cisco delivers the critical infrastructure to help organizations thrive in the AI era. By fusing networking, security, observability, and collaboration, we power how people and technology work together.

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    Picari insights

    Organizations already using Microsoft 365 and seeking an advanced, API-driven email security layer to enhance native protection and gain deeper visibility into internal and external email threats.

    Best for
    • Augmenting Microsoft 365 email security.
    • Detecting advanced phishing and BEC attacks.
    • Gaining visibility into internal mailbox threats.
    May not be ideal if
    • Organizations not using Microsoft 365.
    • As a standalone primary email security gateway.
    • Environments prioritizing inline SMTP gateway control.

    Core capabilities

    Advanced phishing and BEC detection
    Combats phishing and Business Email Compromise using sender authentication, machine learning, and AI engines that model local identity and real-time behavior to block identity deception threats[1][3].
    API-driven threat remediation
    Leverages Microsoft Graph API for fast detection and automated or manual remediation of malicious messages directly from Microsoft 365 mailboxes without changing mail flow[1][3].
    Cisco Talos threat intelligence integration
    Detects and blocks advanced threats like ransomware and QR codes using superior threat intelligence from Cisco Talos, one of the largest threat research teams[1][2].
    Complete email visibility including internal messages
    Provides full visibility into inbound, outbound, and internal user-to-user messages within Microsoft 365 mailboxes using conversation views and message trajectory for contextual threat analysis[1][2].

    Common use cases

    01

    Compliance-focused email security

    02

    Email threat prevention for knowledge workers

    03

    Microsoft 365 environment protection

    Things to consider

    Every product has trade-offs, and which of them matter depends on your environment, your team and your timeline.

    Ask Picari about Cisco Secure Email Threat Defense

    Cisco Secure Email Threat Defense pricing and integrations

    For Cisco Secure Email Threat Defense integration and pricing details, ask Picari. Start a briefing with your question, such as whether it connects to your SIEM, identity provider and ticketing stack, or how it is priced at your seat count and data volume.

    Ask Picari about Cisco Secure Email Threat Defense pricingAsk Picari about Cisco Secure Email Threat Defense integrations

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    Profile last updated on 7 September 2026 by Picari.